I’m very into Keyboard shortcuts.
A while back I wanted to write a global system hook that would allow me to use EMACS/TENEX style navigation bindings (CTRL-E,A,N,P) on normal windows programs. It turns out that somebody already figured out how to do this. Check out this article at LifeHacker on AutoHotKey. Overall, it works perfect and it feels really empowering. You can really put your keyboard to work.
Also, if you want a really comprehensive list of keyboard shortcuts for windows and some of the more popular apps, check this forum post out.